Aspirin- Another mis-understood anti-oxidant?

Conventional nutrition teaches us that our diet should be abundant with antioxidants or the re-classified redox molecules such Vitamin B, C, E glutathione and the like. And it’s not a bad idea too, especially as the body is bombarded with insults on a daily basis in the form of xenoestrogens, toxins, soot in the air, dirty water and all sorts of complex chemicals hidden in our foods. A healthy diet and high nutrient consumption is essential in preventing damage to our DNA through reactive oxygen species or ROS which can contribute to oxidation of fats and other compounds, which contributes to the aging process and exposure to disease development.

Aspirin is one such compound that is often overlooked in the fight against cancer and aging and was a target of the pharmaceutical companies marketing campaign to discredit its benefits, when they decided to bring out a COX 2inhibitor. COX 2 inhibitors help to supress the production of prostaglandins that can be responsible for inflammation, cell degradation, pain and the like. It shouldn’t be lost on anyone that Aspirin which is salicylic and ascetic acid is a natural product that cannot be patented. Therefore it has often been the goal of business lead institutions to discredit many natural substances that cannot be lucratively pursued.

One of the many benefits of Aspirin is its ability to supress lipid peroxidation which is usually mediated by consumption and storage of polyunsaturated fatty acids. When these are stored as body fat in the form of triglycerides and then released in an attempt to stabilise blood sugar levels large amounts of oxidative stress can occur and the use of Asprin, vitamin C and vitamin E can help suppress this form of stress that is heavily linked to heart disease and cancers.  Some of the many unwanted effects of Aspirin such as gastrointestinal stress have been recorded when exceptionally high doses of aspirin have been used in laboratory experiments.

The use of Aspirin shouldn’t be discounted in the fight against disease prevention, however supplementing with Vitamin K would also prove to be beneficial.  To find out more about aging and disease prevention get in touch.


2. Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production.

Candelario-Jalil, Eduardo and Akundi, Ravi S. and Bhatia, Harsharan S. and Lieb, Klaus and Appel, Kurt and Munoz, Eduardo and Hull, Michael and Fiebich, Bernd L. (2006) Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production. [Journal (Paginated)]

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